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Table 3 Assocaition of reproductive factors with incident cardic death

From: Reproductive factors and risk of cardiovascular diseases and all-cause and cardiovascular mortality in American women: NHANES 2003–2018

Reproductive Factors

Age-Adjusted Model

Multivariable Model

HR (95% CI)

P Value

HR (95% CI)

P Value

≤ 11

1.06(0.78–1.44)

0.696

0.97(0.71–1.31)

0.828

12–13

ref

14–15

1.11(0.82–1.51)

0.488

1.00(0.75–1.34)

0.989

≥ 16

1.31(0.91–1.88)

0.141

1.14(0.81–1.60)

0.463

Age at menopause

≤ 44

1.34(0.96–1.87)

0.085

1.21(0.87–1.68)

0.256

35–49

ref

50–54

0.91(0.67–1.24)

0.562

0.94(0.68–1.28)

0.677

≥ 55

0.80(0.54–1.18)

0.260

0.81(0.53–1.22)

0.309

Reproductive lifespan

≤ 32

1.73(1.21–2.49)

0.003

1.62(1.10–2.39)

0.014

33–35

ref

36–38

1.18(0.83–1.69)

0.356

1.19(0.81–1.76)

0.367

39–41

0.97(0.65–1.45)

0.886

1.07(0.71–1.63)

0.739

≥ 42

0.89(0.56–1.41)

0.614

0.91(0.55–1.51)

0.719

Maternal age at first live birth

≤ 19

2.19(1.55–3.09)

0.000

1.63(1.10–2.41)

0.015

21–23

ref

24–26

1.30(0.80–2.12)

0.294

1.45(1.37–2.46)

0.172

≥ 27

1.15(0.69–1.90)

0.595

1.36(1.18–2.44)

0.309

Maternal age at last live birth

≤ 26

1.21(0.69–2.10)

0.504

1.11(0.64–1.92)

0.709

27–29

ref

30–34

1.09(0.60–2.01)

0.774

1.10(0.58–2.07)

0.776

35–39

1.12(0.62-2.00)

0.714

1.09(0.61–1.96)

0.764

≥ 40

1.31(0.77–2.21)

0.315

1.06(0.63–1.78)

0.838

Number of fetation

1

1.44(0.89–2.32)

0.134

1.60(0.97–2.63)

0.067

2

ref

3

1.09(0.75–1.61)

0.644

1.19(0.80–1.76)

0.398

4

1.41(0.94–2.12)

0.096

1.35(0.89–2.05)

0.155

≥ 5

1.40(1.00-1.96)

0.052

1.08(0.75–1.55)

0.666

Age at menarche

1.05(0.98–1.12)

0.188

1.04(0.97–1.11)

0.279

Age at menopause

0.97(0.96–0.99)

0.000

0.98(0.97–0.99)

0.001

Reproductive lifespan

0.97(0.96–0.98)

0.000

0.98(0.97–0.99)

0.000

Maternal age at first live birth

0.95(0.91-1.00)

0.031

1.00(0.95–1.05)

0.976

Maternal age at last live birth

0.98(0.95–1.02)

0.363

0.99(0.96–1.02)

0.470

Number of pregnancies

1.02(0.98–1.07)

0.328

0.96(0.91–1.02)

0.209