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Table 4 Assocaition of reproductive factors with incident death

From: Reproductive factors and risk of cardiovascular diseases and all-cause and cardiovascular mortality in American women: NHANES 2003–2018

Reproductive Factors

Age-Adjusted Model

Multivariable Model

HR (95% CI)

P Value

HR (95% CI)

P Value

≤ 11

1.13(0.97–1.31)

0.116

1.05(0.91–1.22)

0.477

12–13

ref

14–15

1.03(0.88–1.21)

0.731

0.95(0.81–1.12)

0.562

≥ 16

1.16(0.92–1.46)

0.209

1.05(0.83–1.32)

0.687

Age at menopause

≤ 44

1.22(1.03–1.44)

0.021

1.12(0.94–1.34)

0.191

35–49

ref

50–54

0.90(0.76–1.07)

0.247

0.96(0.81–1.15)

0.663

≥ 55

0.87(0.70–1.09)

0.235

0.93(0.72–1.19)

0.542

Reproductive lifespan

≤ 32

1.32(1.07–1.63)

0.010

1.24(0.99–1.57)

0.065

33–35

ref

36–38

1.08(0.84–1.39)

0.525

1.14(0.86–1.51)

0.350

39–41

0.79(0.62–1.02)

0.073

0.88(0.67–1.16)

0.354

≥ 42

1.03(0.80–1.32)

0.840

1.10(0.83–1.46)

0.494

Maternal age at first live birth

≤ 19

1.44(1.17–1.77)

0.000

1.10(0.87–1.39)

0.428

21–23

ref

 

24–26

1.23(0.96–1.57)

0.100

1.37(1.06–1.76)

0.015

≥ 27

0.97(0.73–1.29)

0.840

1.18(0.85–1.62)

0.316

Maternal age at last live birth

≤ 26

1.09(0.87–1.36)

0.462

0.98(0.80–1.22)

0.890

27–29

ref

 

30–34

0.95(0.73–1.23)

0.703

0.96(0.73–1.26)

0.754

35–39

1.22(0.92–1.63)

0.163

1.30(0.99–1.72)

0.061

≥ 40

1.33(0.92–1.91)

0.131

1.18(0.81–1.73)

0.380

Number of pregnancies

1

1.11(0.89–1.39)

0.354

1.16(0.93–1.45)

0.190

2

ref

3

1.03(0.85–1.27)

0.741

1.12(0.91–1.38)

0.271

4

1.17(0.96–1.44)

0.129

1.13(0.92–1.40)

0.242

≥ 5

1.21(1.04–1.42)

0.017

1.00(0.84–1.19)

0.990

Age at menarche

1.00(0.96–1.04)

0.976

0.99(0.96–1.03)

0.672

Age at menopause

0.98(0.97–0.99)

0.000

0.99(0.98-1.00)

0.006

Reproductive lifespan

0.98(0.98–0.99)

0.000

0.99(0.98-1.00)

0.016

Maternal age at first live birth

0.98(0.95-1.00)

0.021

1.02(1.00-1.04)

0.118

Maternal age at last live birth

1.00(0.98–1.01)

0.966

1.01(0.99–1.02)

0.290

Number of pregnancies

1.02(0.99–1.05)

0.160

0.98(0.95–1.01)

0.145