Reproductive Factors | Age-Adjusted Model | Multivariable Model | ||
---|---|---|---|---|
HR (95% CI) | P Value | HR (95% CI) | P Value | |
≤ 11 | 1.13(0.97–1.31) | 0.116 | 1.05(0.91–1.22) | 0.477 |
12–13 | ref | |||
14–15 | 1.03(0.88–1.21) | 0.731 | 0.95(0.81–1.12) | 0.562 |
≥ 16 | 1.16(0.92–1.46) | 0.209 | 1.05(0.83–1.32) | 0.687 |
Age at menopause | ||||
≤ 44 | 1.22(1.03–1.44) | 0.021 | 1.12(0.94–1.34) | 0.191 |
35–49 | ref | |||
50–54 | 0.90(0.76–1.07) | 0.247 | 0.96(0.81–1.15) | 0.663 |
≥ 55 | 0.87(0.70–1.09) | 0.235 | 0.93(0.72–1.19) | 0.542 |
Reproductive lifespan | ||||
≤ 32 | 1.32(1.07–1.63) | 0.010 | 1.24(0.99–1.57) | 0.065 |
33–35 | ref | |||
36–38 | 1.08(0.84–1.39) | 0.525 | 1.14(0.86–1.51) | 0.350 |
39–41 | 0.79(0.62–1.02) | 0.073 | 0.88(0.67–1.16) | 0.354 |
≥ 42 | 1.03(0.80–1.32) | 0.840 | 1.10(0.83–1.46) | 0.494 |
Maternal age at first live birth | ||||
≤ 19 | 1.44(1.17–1.77) | 0.000 | 1.10(0.87–1.39) | 0.428 |
21–23 | ref | |||
24–26 | 1.23(0.96–1.57) | 0.100 | 1.37(1.06–1.76) | 0.015 |
≥ 27 | 0.97(0.73–1.29) | 0.840 | 1.18(0.85–1.62) | 0.316 |
Maternal age at last live birth | ||||
≤ 26 | 1.09(0.87–1.36) | 0.462 | 0.98(0.80–1.22) | 0.890 |
27–29 | ref | |||
30–34 | 0.95(0.73–1.23) | 0.703 | 0.96(0.73–1.26) | 0.754 |
35–39 | 1.22(0.92–1.63) | 0.163 | 1.30(0.99–1.72) | 0.061 |
≥ 40 | 1.33(0.92–1.91) | 0.131 | 1.18(0.81–1.73) | 0.380 |
Number of pregnancies | ||||
1 | 1.11(0.89–1.39) | 0.354 | 1.16(0.93–1.45) | 0.190 |
2 | ref | |||
3 | 1.03(0.85–1.27) | 0.741 | 1.12(0.91–1.38) | 0.271 |
4 | 1.17(0.96–1.44) | 0.129 | 1.13(0.92–1.40) | 0.242 |
≥ 5 | 1.21(1.04–1.42) | 0.017 | 1.00(0.84–1.19) | 0.990 |
Age at menarche | 1.00(0.96–1.04) | 0.976 | 0.99(0.96–1.03) | 0.672 |
Age at menopause | 0.98(0.97–0.99) | 0.000 | 0.99(0.98-1.00) | 0.006 |
Reproductive lifespan | 0.98(0.98–0.99) | 0.000 | 0.99(0.98-1.00) | 0.016 |
Maternal age at first live birth | 0.98(0.95-1.00) | 0.021 | 1.02(1.00-1.04) | 0.118 |
Maternal age at last live birth | 1.00(0.98–1.01) | 0.966 | 1.01(0.99–1.02) | 0.290 |
Number of pregnancies | 1.02(0.99–1.05) | 0.160 | 0.98(0.95–1.01) | 0.145 |