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Table 1 Selected demographics and clinical characteristics (per-protocol set)

From: Efficacy and safety of eliapixant in endometriosis-associated pelvic pain: the randomized, placebo-controlled phase 2b SCHUMANN study

 

Eliapixant 25 mg BID

n = 37 (100%)

Eliapixant 75 mg BID

n = 37 (100%)

Eliapixant 150 mg BID

n = 36 (100%)

Placebo

n = 36 (100%)

Elagolix

150 mg

n = 37 (100%)

Total

n = 183 (100%)

Race

      

 White

26 (70.3%)

26 (70.3%)

25 (69.4%)

23 (63.9%)

35 (94.6%)

135 (73.8%)

 Black or African American

0

1 (2.7%)

2 (5.6%)

2 (5.6%)

0

5 (2.7%)

 Asian

11 (29.7%)

10 (27.0%)

9 (25.0%)

11 (30.6%)

0

41 (22.4%)

 Not reported

0

0

0

0

2 (5.4%)

2 (1.1%)

Age (years)

33.41 (7.07)

36.32 (7.60)

35.75 (7.11)

35.58 (7.17)

32.19 (6.64)

34.64 (7.22)

Age group

      

 < 30 years

11 (29.7%)

7 (18.9%)

7 (19.4%)

10 (27.8%)

14 (37.8%)

49 (26.8%)

 30–40 years

20 (54.1%)

18 (48.6%)

21 (58.3%)

14 (38.9%)

19 (51.4%)

92 (50.3%)

 > 40–55 years

6 (16.2%)

12 (32.4%)

8 (22.2%)

12 (33.3%)

4 (10.8%)

42 (23.0%)

Main eye color

      

 Green

4 (10.8%)

8 (21.6%)

7 (19.4%)

8 (22.2%)

12 (32.4%)

39 (21.3%)

 Blue

8 (21.6%)

7 (18.9%)

6 (16.7%)

5 (13.9%)

10 (27.0%)

36 (19.7%)

 Gray

1 (2.7%)

2 (5.4%)

3 (8.3%)

1 (2.8%)

2 (5.4%)

9 (4.9%)

 Hazel

1 (2.7%)

1 (2.7%)

4 (11.1%)

4 (11.1%)

0

10 (5.5%)

 Brown

23 (62.2%)

19 (51.4%)

16 (44.4%)

18 (50.0%)

13 (35.1%)

89 (48.6%)

Natural hair color (at age 18)

      

 Red

0

1 (2.7%)

1 (2.8%)

0

0

2 (1.1%)

 Blonde

7 (18.9%)

4 (10.8%)

8 (22.2%)

7 (19.4%)

8 (21.6%)

34 (18.6%)

 Light brown

9 (24.3%)

10 (27.0%)

8 (22.2%)

8 (22.2%)

14 (37.8%)

49 (26.8%)

 Dark brown

10 (27.0%)

13 (35.1%)

7 (19.4%)

6 (16.7%)

14 (37.8%)

50 (27.3%)

 Black

11 (29.7%)

9 (24.3%)

12 (33.3%)

15 (41.7%)

1 (2.7%)

48 (26.2%)

Body mass index (kg/m2)

25.08 (6.53)

26.01 (5.17)

25.34 (5.24)

25.61 (6.18)

25.64 (6.44)

25.53 (5.89)

Mean worst pain

6.09 (1.73)

6.05 (1.78)

6.63 (1.62)

5.89 (1.93)

6.38 (1.78)

6.21 (1.77)

Non-menstrual pelvic pain

5.85 (1.81)

5.80 (1.95)

6.45 (1.78)

5.62 (2.05)

6.18 (1.86)

5.98 (1.89)

Dysmenorrhea

7.16 (1.60)

6.91 (1.55)

7.38 (1.39)

7.00 (1.77)

7.29 (1.84)

7.15 (1.63)

  1. Abbreviations: BID twice daily, SD standard deviation
  2. Data are expressed as mean (SD) unless otherwise stated