Fig. 3

Trajectories of WBC indicators around the final menstrual period in each subgroup of baseline BMI. Graphs show the estimated means of each WBC indicators by the piece-wise linear mixed-effect model with each model covariate set at its analysis sample mean in each subgroup of baseline body mass index (normal weight, overweight, and obesity). Models were adjusted for age at checkup (continuous), educational level, smoking status, alcohol consumption, physical activity, hypertension history and anti-hypertensive medication, diabetes history and anti-diabetic medication, dyslipidemia history and lipid-lowering medication, body mass index (continuous), and hemoglobin (continuous) as fixed effects. Solid line and dashed lines represent mean values and 95% CI, respectively. Abbreviations: BMI, body mass index; FMP, final menstrual period; WBC, white blood cells; TWBC, total white blood cells; NEUT, neutrophils; LYM, lymphocytes; MON, monocytes