From: Trajectories of peripheral white blood cells count around the menopause: a prospective cohort study
Variables | 1st Checkup (2006–2007) | 2nd Checkup (2008–2009) | 3rd Checkup (2010–2011) | 4th Checkup (2012–2013) | 5th Checkup (2014–2015) | 6th Checkup (2016–2017) | 7th Checkup (2018–2020) |
---|---|---|---|---|---|---|---|
Na | 3339 | 2984 | 3151 | 2993 | 2703 | 2582 | 2483 |
Age at checkupb, y, mean (SD) | 46.16 (4.10) | 47.67 (4.58) | 49.40 (4.68) | 51.60 (4.68) | 53.70 (4.75) | 56.34 (4.56) | 57.78 (4.45) |
Education levelb, n (%) | |||||||
Junior high school or below | 2310 (69.22) | 1983 (66.45) | 2103 (66.74) | 1994 (66.62) | 1804 (66.77) | 1790 (69.35) | 1650 (66.51) |
Senior high school or above | 1027 (30.78) | 1001 (33.55) | 1048 (33.26) | 999 (33.38) | 898 (33.23) | 791 (30.65) | 831 (33.49) |
Missing | 2 | 0 | 0 | 0 | 1 | 1 | 2 |
Smoking statusb, n (%) | |||||||
Never | 3279 (98.20) | 2928 (98.12) | 3099 (98.35) | 2945 (98.40) | 2667 (98.67) | 2546 (98.61) | 2447 (98.55) |
Previous | 15 (0.45) | 15 (0.50) | 12 (0.38) | 12 (0.40) | 9 (0.33) | 8 (0.31) | 9 (0.36) |
Current | 45 (1.35) | 41 (1.37) | 40 (1.27) | 36 (1.20) | 27 (1.00) | 28 (1.08) | 27 (1.09) |
Alcohol consumptionb, n (%) | |||||||
No | 3104 (92.96) | 2728 (91.54) | 2973 (94.38) | 2831 (94.75) | 2549 (94.41) | 2443 (94.84) | 2336 (94.46) |
Occasional | 224 (6.71) | 240 (8.05) | 169 (5.37) | 143 (4.79) | 139 (5.15) | 121 (4.70) | 129 (5.22) |
Often | 11 (0.33) | 12 (0.40) | 8 (0.25) | 14 (0.47) | 12 (0.44) | 12 (0.47) | 8 (0.32) |
Missing | 0 | 4 | 1 | 5 | 3 | 6 | 10 |
Physical activityb, n (%) | |||||||
Inactive | 182 (5.47) | 541 (18.19) | 968 (30.78) | 961 (32.21) | 869 (32.20) | 766 (29.83) | 791 (32.00) |
Occasional | 2828 (84.95) | 1887 (63.45) | 1767 (56.18) | 1703 (57.07) | 1556 (57.65) | 1522 (59.27) | 1426 (57.69) |
Active | 319 (9.58) | 546 (18.36) | 410 (13.04) | 320 (10.72) | 274 (10.15) | 280 (10.90) | 255 (10.32) |
Missing | 10 | 10 | 6 | 9 | 4 | 14 | 11 |
Diabetes history and anti-diabetic medicationb, n (%) | |||||||
No diabetes history | 3164 (94.82) | 2776 (93.06) | 2888 (91.65) | 2687 (89.93) | 2367 (88.22) | 2210 (85.76) | 2079 (84.44) |
Diabetes history with no medication | 131 (3.93) | 112 (3.75) | 168 (5.33) | 204 (6.83) | 215 (8.01) | 268 (10.40) | 262 (10.64) |
Diabetes history with medication | 42 (1.26) | 68 (2.28) | 86 (2.73) | 82 (2.74) | 61 (2.27) | 97 (3.76) | 99 (4.02) |
Diabetes history with medication missing | 0 (0) | 27 (0.91) | 9 (0.29) | 15 (0.50) | 40 (1.49) | 2 (0.08) | 22 (0.89) |
Missing | 2 | 1 | 0 | 5 | 20 | 5 | 21 |
Hypertension history and anti-hypertensive medicationb, n (%) | |||||||
No hypertension history | 2662 (79.77) | 2201 (73.81) | 2189 (69.47) | 1951 (65.21) | 1645 (61.15) | 1453 (56.41) | 1319 (53.34) |
Hypertension history with no medication | 471 (14.11) | 519 (17.40) | 676 (21.45) | 763 (25.50) | 770 (28.62) | 877 (34.05) | 839 (33.93) |
Hypertension history with medication | 154 (4.61) | 204 (6.84) | 274 (8.70) | 256 (8.56) | 189 (7.03) | 241 (9.36) | 247 (9.99) |
Hypertension history with medication missing | 50 (1.50) | 58 (1.95) | 12 (0.38) | 22 (0.74) | 86 (3.20) | 5 (0.19) | 68 (2.75) |
Missing | 2 | 2 | 0 | 1 | 13 | 6 | 10 |
Dyslipidemia history and lipid-lowering medicationb, n (%) | |||||||
No dyslipidemia history | 2500 (74.87) | 1981 (66.39) | 1925 (61.09) | 1633 (54.58) | 1331 (49.30) | 1148 (44.46) | 973 (39.19) |
Dyslipidemia history with no medication | 699 (20.93) | 995 (33.34) | 1199 (38.05) | 1320 (44.12) | 1298 (48.07) | 1428 (55.31) | 1387 (55.86) |
Dyslipidemia history with medication | 10 (0.30) | 8 (0.27) | 27 (0.86) | 17 (0.57) | 13 (0.48) | 6 (0.23) | 48 (1.93) |
Dyslipidemia history with medication missing | 130 (3.89) | 0 (0) | 0 (0) | 22 (0.74) | 58 (2.15) | 0 (0) | 75 (3.02) |
Missing | 0 | 0 | 0 | 1 | 3 | 0 | 0 |
BMIb, kg/m2, mean (SD) | 24.58 (3.39) | 24.56 (3.35) | 24.82 (3.36) | 24.81 (3.30) | 24.79 (3.24) | 24.79 (3.35) | 24.72 (3.42) |
Hb, g/L, mean (SD) | 132.75 (13.32) | 129.46 (12.98) | 133.58 (12.59) | 134.60 (11.97) | 135.87 (11.47) | 136.06 (10.19) | 136.25 (9.86) |