Table 3 Annual changes in WBC in relation to the FMP across baseline age subgroups a
From: Trajectories of peripheral white blood cells count around the menopause: a prospective cohort study
WBC indicators | Baseline age < 45 years | Baseline age ≥ 45 years | ||||
|---|---|---|---|---|---|---|
Obs. d | β (SE) | P Value | Obs. d | β (SE) | P Value | |
NEUT, ×109 /L | ||||||
Time segments relative to FMP | ||||||
A. < -5 y relative to FMP | 2,918 | 0.010(0.012) | 0.3748 | 685 | -0.005(0.025) | 0.8369 |
B. -5 ∼ -4 y relative to FMP | 703 | 0.033(0.039) | 0.3872 | 356 | -0.054(0.057) | 0.3471 |
C. -4 ∼ + 2 y relative to FMP | 3,668 | -0.087(0.010) | < 0.0001 | 4,113 | -0.030 (0.010) | 0.0020 |
D. +2 ∼ + 6 y relative to FMP | 1,562 | 0.004(0.013) | 0.7287 | 2,588 | 0.004(0.011) | 0.7270 |
E. > +6 y relative to FMP | 538 | -0.015(0.025) | 0.5424 | 2,504 | 0.022(0.010) | 0.0338 |
LYM, ×109/L | ||||||
Time segments relative to FMP | ||||||
A. < -5 y relative to FMP | 2,957 | -0.019(0.005) | 0.0003 | 690 | -0.012(0.011) | 0.2552 |
B. -5 ∼ -1 y relative to FMP | 2,666 | 0.000(0.005) | 0.9976 | 2,251 | -0.021(0.006) | 0.0008 |
C. > -1 y relative to FMP | 3,861 | 0.009(0.004) | 0.0426 | 7,397 | 0.002(0.004) | 0.7191 |
MON, ×109/L | ||||||
Time segments relative to FMP | ||||||
A. < -4 y relative to FMP | 3,614 | -0.006(0.001) | < 0.0001 | 1,036 | -0.016(0.004) | < 0.0001 |
B. -4 ∼ + 2 y relative to FMP | 3,658 | -0.001(0.001) | 0.2648 | 4,105 | -0.009(0.001) | < 0.0001 |
C. > +2 y relative to FMP | 2,068 | -0.000(0.001) | 0.9775 | 5,034 | 0.004(0.001) | < 0.0001 |