Table 5 Results from linear regression analyses for the associations between preterm birth status and age at events related to menarche and menopause

Menarche-related

Age at first regular period

Unadjusted (n=72,616)

-0.037 (0.02)

Ref

0.17

Adj. for demographics (n=79,796)

-0.024 (0.03)

Ref

0.36

Adj. for demographic and lifestyle factors (n=61,348)

-0.022 (0.03)

Ref

0.43

Age at menarche

Unadjusted (n=86,575)

-0.055 (0.02)

Ref

0.02

Adj. for demographics (n=83,156)

-0.026 (0.02)

Ref

0.28

Adj. for demographic and lifestyle factors (n=72,719)

-0.031 (0.03)

Ref

0.23

Reproductive window

Reproductive window (years)

Unadjusted (n=60,412)

-0.629 (0.16)

Ref

< 0.0001

Adj. for demographics (n=58,165)

-0.532 (0.17)

Ref

0.001

Adj. for demographic and lifestyle factors (n=51,037)

-0.418 (0.17)

Ref

0.006

Menopause-related

Age at last regular period

Unadjusted (n=78,268)

-0.624 (0.16)

Ref

< 0.0001

Adj. for demographics (n=75,352)

-0.446 (0.16)

Ref

0.005

Adj. for demographic and lifestyle factors (n=66,082)

-0.397 (0.17)

Ref

0.02

Age at last vaginal bleeding

Unadjusted (n=79,664)

-0.746 (0.17)

Ref

< 0.0001

Adj. for demographics (n=76,671)

-0.533 (0.17)

Ref

0.002

Adj. for demographic and lifestyle factors (n=67,194)

-0.435 (0.18)

Ref

0.02

Age at natural menopause

Unadjusted (n=68,889)

-0.682 (0.15)

Ref

< 0.0001

Adj. for demographics (n=66,291)

-0.531 (0.15)

Ref

0.0004

Adj. for demographic and lifestyle factors (n=58,084)

-0.506 (0.16)

Ref

0.001

Age at natural menopause (conservative)

Unadjusted (n=60,487)

-0.681 (0.16)

Ref

< 0.0001

Adj. for demographics (n=58,234)

-0.543 (0.16)

Ref

0.0008

Adj. for demographic and lifestyle factors (n=51,092)

-0.493 (0.17)

Ref

0.004