Table 1 Characteristic of luminal B breast cancer patients with and without malignant pleural effusions
Variables | With MPE (n = 54) | Without MPE (n = 87) | P |
|---|---|---|---|
Age at surgery (years) | 0.096 | ||
< 50 | 32 (59.3%) | 39(44.8%) | |
≥ 50 | 22(40.7%) | 48 (55.2%) | |
Primary tumor location | |||
Left | 25 (46.3%) | 50 (57.5%) | 0.186 |
Right | 26 (48.1%) | 36 (41.4%) | |
Bilateral | 3 (5.6%) | 1 (1.1%) | |
Clinical stages at initial diagnosis | |||
Stage I | 5 (9.3%) | 11 (12.6%) | 0.088 |
Stage II | 15 (27.8%) | 26 (29.9%) | |
Stage III | 22 (44.4%) | 36 (41.4%) | |
Unknown | 10 (18.5%) | 4 (4.6%) | |
Histological type | |||
Invasive ductal carcinoma | 50 (92.6%) | 83 (95.4%) | 0.787 |
Invasive lobular carcinoma | 1(1.9%) | 1(1.1%) | |
Others | 3 (5.6%) | 3 (3.4%) | |
HER-2 | |||
Positive | 8 (14.9%) | 12 (13.8%) | 0.866 |
Negative | 46 (85.2%) | 75 (86.2%) | |
Metastatic site | 0.502 | ||
Lung | 22(40.7%) | 29(33.3%) | |
Liver | 12(22.2%) | 24(27.6%) | |
Bone | 27(50.0%) | 28(32.2%) | |
Others | 42(77.8%) | 50(57.5%) | |
Neoadjuvant therapy | |||
Yes | 11 (20.3%) | 13 (14.9%) | 0.404 |
No | 43 (79.6%) | 74 (85.0%) | |
Adjuvant Therapy | |||
Chemotherapy | 45 (83.3%) | 68 (78.2%) | 0.316 |
Endocrine therapy | 34 (63.0%) | 51 (58.6%) | |
Radiotherapy | 24 (44.4%) | 22 (25.3%) | |
Surgical approach | |||
Radical surgery | 49 (83.3%) | 84 (96.6%) | 0.260 |
Conservative surgery | 5 (9.3%) | 3 (3.4%) |