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Table 3 Differences in serum inflammatory levels among participants with different severity of depression

From: Associations between serum cytokine levels and postmenopausal depression in postmenopausal women with and without menopause hormone therapy

 

Variable

 

Non-depression

Mild depression

Moderate depression

Severe depression

Statistics

P

 

n

93

30

12

1

  

Total(n = 236)

IL-1β(pg/ml)

0(0, 132.88)

0(0, 64.52)

2.95(0, 43.70)

58.4

h = 7.926

0.048

IL-6(pg/ml)

1.58(0, 237.92)

0(0, 385.97)

0(0, 30.07)

0

h = 6.211

0.102

TNF-α(pg/ml)

0(0, 361.77)

5.76(0, 543.46)

62.60(0, 440.37)

271.94

h = 8.392

< 0.001

IL-18(ng/L)

20.82 ± 12.13

32.13 ± 33.88

56.78 ± 46.17

83.81

f = 11.398

< 0.001

 

n

57

25

11

1

  

POST (n = 94)

IL-1β(pg/ml)

0 (0, 132.88)

0(0, 64.52)

2.49(0, 43.70)

58.4

h = 4.263

0.234

IL-6(pg/ml)

1.10 (0, 237.92)

0(0, 385.97)

0(0, 30.07)

0

h = 1.528

0.677

TNF-α(pg/ml)

0(0, 361.77)

7.24 (0, 543.46)

71.67 (5.93, 440.37)

271.94

h = 26.240

< 0.001

IL-18(ng/L)

27.63 ± 25.74

19.96 ± 13.93

59.82 ± 47.15

83.81

f = 7.247

< 0.001

 

n

36

5

1

0

  

POST + MHT (n = 42)

IL-1β(pg/ml)

0(0, 40.55)

0(0, 2.24)

12.9

-

h = 3.814

0.148

IL-6(pg/ml)

0(0, 50.46)

0(0, 0)

3.35

-

h = 4.2

0.122

TNF-α(pg/ml)

0(0, 120.04)

0(0, 8.77)

0

-

h = 0.785

0.675

IL-18(ng/L)

21.09 ± 164.67

13.37 ± 49.25

23.32

-

f = 0.888

0.42