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Table 3 Results of the bivariable and multivariable cox regression analysis of ovarian cancer patients’ death according to waiting time

From: The effect of waiting time on ovarian cancer survival in oncology centres, Addis Ababa, Ethiopia: a retrospective cohort study

Covariates

Category

Bivariable

CHR (95%CI)

Multivariable AHR (95%CI)

P-value

Waiting time

≤ 10 weeks

1

1

 
 

> 10 weeks

1.69(1.32–2.15)*

1.36(1.05–1.75)**

0.019

Age at diagnosis

< 30

1

1

 

30–39

1.72(0.79–3.72)

0.77(0.32–1.84)

0.550

40–49

3.30(1.67–6.54)*

1.24(0.53–2.91)

0.626

50–59

4.57(2.30–9.07)*

1.75(0.63–4.85)

0.281

≥ 60

9.13(4.79–17.39)*

2.84(1.04–7.73)**

0.042

Number of parity

0–1

1

1

 

2–3

1.64(1.14–2.37)*

0.92(0.61–1.38)

0.686

≥ 4+

1.92(1.41–2.62)*

0.69(0.47–1.01)

0.052

Menopausal status

Premenopausal

1

1

 

Postmenopausal

3.27(2.41–4.44)*

0.71(0.39–1.27)

0.246

Family history of ovarian cancer

Yes

1

1

 

No

0.49(0.27–0.89)*

0.71(0.37–1.34)

0.287

Unknown

1.78(1.08–2.91)*

0.97(0.55–1.72)

0.924

FIGO stage at diagnosis

Stage I

1

1

 

Stage II

1.51(0.74–3.07)

1.51(0.74–3.09)

0.264

Advanced

(III & IV)

7.74(4.19–14.27)*

2.27(1.17–4.39)**

0.015

Histologic type

Sex-cord stromal

1

1

 

Epithelial

23.49(3.29–167.5)*

9.05(1.24–66.13)**

0.030

Germ cell

3.37(0.39–28.86)

4.59(0.51–41.41)

0.175

Others

2.51(0.16–40.19)

2.26(0.14–36.94)

0.568

Comorbidity

No

1

1

 

Yes

1.82(1.42–2.33)*

1.48(1.13–1.95)**

0.005

Combined oral contraceptive user status

Non-user

1

1

 

User

0.45(0.22–0.92)*

0.72(0.34–1.55)

0.405

Unknown

2.06(1.61–2.64)*

1.81(1.38–2.37)**

< 0.001

Treatment completed

Yes

1

1

 

No

6.13(4.45–8.44)*

3.19(2.23–4.56)**

< 0.001

Pain medication received

Yes

1

1

 

No

0.55(0.43–0.70)*

0.86(0.65–1.13)

0.275

  1. AHR; adjusted Hazard ratio, CI; confidence interval, CHR: crude hazard ratio, * and ** indicate: significantly associated variables in bivariable and multivariable analysis (𝑃 < 0.05).