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Table 3 Diagnostic accuracy of indicators for NAFLD in overweight and obese PCOS patients

From: Biochemical, sex hormonal, and anthropometric predictors of non-alcoholic fatty liver disease in polycystic ovary syndrome

Variables

AUC (95% CI)

P-value

Cut-off value

Sensitivity

Specificity

PPV

NPV

BMI (kg/m2)

0.761 (0.658–0.864)

< 0.001

26.8

79.7% (47/59)

64.3% (18/28)

82.5% (47/57)

60.0% (18/30)

AC (cm)

0.721 (0.609–0.833)

0.001

88.3

76.3% (45/59)

57.1% (16/28)

78.9% (45/57)

53.3% (16/30)

Triglyceride (mmol/L)

0.738 (0.620–0.856)

< 0.001

1.57

71.2% (42/59)

75.0% (21/28)

85.7% (42/49)

55.3% (21/38)

TC (mmol/L)

0.670 (0.546–0.793)

0.011

4.67

69.5% (41/59)

64.3% (18/28)

80.4% (41/51)

50.0% (18/36)

HDL-C (mmol/L)

0.613 (0.481–0.744)

0.091

-

    

LDL-C (mmol/L)

0.667 (0.549–0.784)

0.012

3.31

47.5% (28/59)

89.3% (25/28)

90.3% (28/31)

44.6% (25/56)

Glucose (mmol/l)

0.683 (0.554–0.812)

0.006

4.83

84.7% (50/59)

50.0% (14/28)

78.1% (50/64)

60.9% (14/23)

Insulin (pmol/L)

0.748 (0.643–0.853)

< 0.001

111.35

52.5% (31/59)

92.9% (26/28)

93.9% (31/33)

48.1% (26/54)

FT (pg/mL)

0.674 (0.550–0.798)

0.009

7.60

66.1% (39/59)

71.4% (20/28)

83.0% (39/47)

50.0% (20/40)

SHBG (nmol/L)

0.737 (0.621–0.853)

< 0.001

25.0

61.0% (36/59)

82.1% (23/28)

87.8% (36/41)

50.0% (23/46)

  1. Bold font indicates statistical significance (p < 0.05)
  2. AC, abdominal circumference; AUC, area under the curve; BMI, body mass index; CI, confidence interval; FT, free testosterone; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NAFLD, non-alcoholic fatty liver disease; NPV, negative predictive value; PCOS, polycystic ovary syndrome; PPV, positive predictive value; SHBG, sex hormone-binding globulin; TC, total cholesterol