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Table 2 Association between number of ELNs and accurate nodal migration at the cutoff point of 13 with train cohort

From: Construction and validation of a novel nomogram for prediction of lymph node metastasis in HER2-positive breast cancer: based on the optimal number of examined lymph nodes for accurate nodal staging

 

Univariate logistic analysis

Multivariate logistic analysis

Variables

OR (95%CI)

p

OR (95%CI)

P

Age

    

< 59

Reference

   

>=59

0.85(0.72-1.00)

0.05

  

Race

    

White

Reference

   

Black

0.83(0.65–1.05)

0.12

  

Other

0.86(0.68–1.11)

0.25

  

Radiation

    

Yes

Reference

 

Reference

 

No/Unknown

0.07(0.06–0.10)

< 0.001

0.11(0.08–0.15)

< 0.001

Chemotherapy

    

Yes

Reference

 

Reference

 

No/Unknown

0.36(0.30–0.43)

< 0.001

0.58(0.47–0.71)

< 0.001

T stage

    

T1

Reference

 

Reference

 

T2

3.37(2.83–4.04)

< 0.001

2.43(1.99–2.98)

< 0.001

T3

6.91(4.81–9.91)

< 0.001

4.09(2.75–6.07)

< 0.001

T4

6.57(3.83–11.27)

< 0.001

5.91(3.28–10.65)

< 0.001

N stage

    

N0

    

N1

 

0.99

  

N2

 

0.99

  

N3

 

1

  

Grade

    

I

Reference

 

Reference

 

II

2.88(1.85–4.48)

< 0.001

2.07(1.22–3.50)

0.01

III

5.31(3.44–8.19)

< 0.001

3.09(1.84–5.18)

< 0.001

IV

1.76(0.24–13.1)

0.58

0.72(0.06–8.16)

0.79

ER

    

Negative

1.03(0.87–1.22)

0.72

  

Positive

Reference

   

PR

    

Negative

1.03(0.87–1.20)

0.76

  

Positive

Reference

   

ELNs

    

< 13

Reference

 

Reference

 

>=13

3.77(3.14–4.52)

< 0.001

2.93(2.39–3.59)

< 0.001

  1. Note: ELNs: examined lymph nodes; ER, estrogen receptor; PR, progesterone receptor; OR, odds ratio